Botanical Name of Pterocarpus : Pterocarpus marsupium Family : Fabaceae Synonyms of Pterocarpus: Hindi - Vijaisar kaashtha English - Indian kinowood Sanskrit - Pitasala Asana, … HPTLC of n-hexane, ethyl acetate and ethanol extracts of heart wood and small branches showed different phytochemical profile. Pterocarpus marsupium Roxb., a medicinal plant, known for its anti-oxidant and anti-diabetic activity is a rich source of phytochemicals with antihyperglycemic and antihyperlipidemic … These include, Allium sativum, Eugenia jambolana, Momordica charantia Ocimum sanctum, Phyllanthus amarus, Pterocarpus marsupium… Diabetes: Holy basil might lower blood sugar levels. The results of the test drug were compared with the standard drug.Results: Ethanolic seed extract of Pterocarpus marsupium at 100 mg/kg and 200 mg/kg had significantly reduced the blood glucose level compared to disease control rats on day 1, 7, 14 and 21. This might interfere with controlling blood sugar levels. It is well known to Ayurvedic medicine because of its curative and lenitive properties. The aim of the study was to evaluate the effect of Pterocarpus marsupium (PM) on acetic acid (AA)-induced ulcerative colitis (UC) in rats. Pterocarpus marsupium shows significant decrease in triglycerides levels, serum cholesterol levels, LDL levels and increased HDL levels, total protein levels compared to the disease control group.Conclusions: In conclusion, the present study shows that the ethanolic seed extract of Pterocarpus marsupium has potential antidiabetic action in gabapentin induced diabetic rats and the effect was found to be more similar to the standard drug metformin. Various parts of the P. marsupium tree (heartwood, leaves and flowers) have long been used for their medicinal properties in Ayurveda. History showed that medicinal plants have been used in traditional healing around the world for a long time to treat diabetes; this is because such herbal plants have hypoglycemic properties and other beneficial properties, as reported in scientific literature. According to the ancient Ayurvedic texts, the bark of the Vijaysar tree is helpful in diarrhoea, diabetes …  , Bose SN, Sepaha GC (1956) Clinical observations on the antidiabetic, against carbon tetrachloride induced dam-, Hilal A, Kalyanaraman R (2015) Pharmacology of, Pradhan S, Sahu SK, Panda SK, Mishra SS, Chinar, by LC–MS techniques and its in-vitro lipid lowering activity, Haranath PS, Ranganatha Rao K, Anjaneyulu CR, Ramanathan JD,          , Jain SC, Sharma SK, Kumar R, Rajwanshi VK, Babu BR (1997) A homoi-, Handa SS, Singh R, Maurya R, Satti NK, Suri KA, et al. International Journal of Pharmacy and Pharmaceutical Sciences, Research Journal of Pharmacognosy and Phytochemistry. The 200 mg/kg had more pronounced effect on postprandial hyperglycemia. It turns the water blue as soon as it comes in … Detaillierte Informationen im Zusammenhang mit … Its bark is known as "The miracle cure for diabetes". 12 The heartwood is used in the treatment of inflammation and reported to have medicinal importance in the management of diabetes … Buy Panchaveda Pterocarpus Marsupium 400 mg Extract (120 Veg Capsules) Organic Natural Ayurvedic Herbal Diabetes Blood Sugar Support Supplement, Vijaysar Indian Kino Tree Helps Bad … Anti-diabetic activity wasevaluated on experimental model byDelhi Institute of Pharmaceutical Sciences and Research (DIPSAR). Also the phytoextract at the concentration of 10–320 μg/ml was evaluated for its antioxidant potential by in-vitro antioxidant assays which includes, determination of total phenol content; reducing power assay; nitric oxide scavenging activity; superoxide radical scavenging activity; total antioxidant capacity; total flavonoid content; DPPH scavenging activity; and hydrogen peroxide scavenging activity. Pterocarpus marsupium Roxb., a medicinal plant, known for its anti-oxidant and anti-diabetic activity is a rich source of phytochemicals with antihyperglycemic and antihyperlipidemic activities. It has a long history of numerous traditional and ethno-botanical applications in diverse cultures. (2000) Pterocar-, Anandharajan R, Pathmanathan K, Shankernar, extracts on clinical and standards strains of, Majeed M, Bani S, Natarajan S, Pandey A (2017) E, Track the below URL for one-step submission, https://juniperpublishers.com/online-submission.php. A new C-glucosyl-alpha-hydroxydihydrochalcone derivative, (aS)-3'-C-ff-glucopyranosyl-a,3,4,2'4'-pentahydroxydihydrochalcone, named as bijayasaline (1) was isolated from the heartwood of Bijayasal (Pterocarpus marsupium) and characterized on the basis of NMR and circular dichroism (CD) spectral data. PM extract 100 mg and 200 mg/kg was given orally to groups four and five, respectively, and standard drug sulfasalazine (100 mg/kg, p.o) to group three. The alcoholic extract of P. marsupium was evaluated for advanced glycation-end-products formation, erythrocyte sorbitol accumulation and rat kidney aldose reductase enzyme inhibition at the concentration of 25–400 μg/ml using in-vitro bioassays. This essay details the vijaysar uses for health, formulations, dosage and side effects. Blood glucose level, serum triglycerides, total cholesterol, HDL cholesterol and LDL cholesterol were evaluated in gabapentin induced diabetic rats. So work is carried out to establish preliminary physicochemical and phytochemical standards of small branches of P. marsupium. ãFQ†0††{L™"^Ež3±±¨1j3–1. in a neonatal rat model. The standard parameters of small branches of P. marsupium have not been prepared yet. The bark is also used for bleeding and toothaches. Pterocarpus marsupium reduces blood sugar level, cholesterol and triglycerides. The rats were divided into five groups, each having six rats. A list of medicinal plants with proven antidiabetic and related beneficial effects and of herbal drugs used in treatment of diabetes is compiled. UC was induced by administering AA (3 % v/v of 2 ml) to all the animals except group one. Water is kept in the wooden glass of its bark overnight and that water is consumed by diabetes … The present investigation suggests that the phytoextract showed prominent antioxidant, antiglycation property and, inhibited accumulation of sorbitol and ALR enzyme, thus promising a beneficial role in reducing/delaying diabetic complications. For the reproductive toxicity study forty Wistar rats of each sex (80 rats) divided into four dosage groups received 0 (vehicle control), 20 (low dose), 100 (mid dose) and 200 (high dose) mg/kg bwt/day of 3'-HPT respectively for a period of two weeks while pre-mating, mating, on the day before sacrifice, in females during pregnancy and four days of lactation period. Pterocarpus marsupium contain acids that reduce intestinal absorption of glucose, stimulate the pancreas to increase insulin production, and decrease sugar craving by causing sugar to taste like grit or sandpaper. Difference in HPTLC profiles suggests that small branches cannot be used in place of heart wood and further research is required to find out the substitute for heart wood of P. marsupium. Our ancestors used the barks and heartwood of Vijaysar tree in various forms to control diabetes. 3'-Hydroxypterostilbene (3'-HPT) is one of the active constituents of Sphaerophysa salsula and Pterocarpus marsupium. It is … It is now considered as a valuable source of unique natural products for development of medicines against various diseases and for the development of industrial products. Pterocarpus Marsupium is used for Diabetes, Hyperglycemia and other conditions. Group two served as UC control animals, and group one control animals received vehicle for 7 days. Diabetes mellitus (DM), both insulin-dependent DM (IDDM) and non-insulin dependent DM (NIDDM) is a common and serious metabolic disorder throughout the world. These studies play the drug as a novel candidate for bioprospection and drug development for treatment of diseases such as cancer, diabetes, cataract, ulcer, dementia… Among many medications and other alternative medicines, several herbs have been known to cure and control diabetes; additionally they have no side effects. The present work investigated 90 day repeated oral dose and reproductive (developmental) toxicity of 3'-HPT as a test substance in rats as per OECD guidelines. Pterocarpus marsupium may lower blood sugar through an unrelated pathway of that of insulin. Vijaysar continues to be used for diabetics … Aqueous extract of the wood of this plant has a long history to be used in treatment of diabetes mellitus. Pterocarpus marsupium is a medicinal plant used in Ayurvedic system of medicine to control blood sugar and strong antidiabetic. Total phenolic contents of heart wood and small branches in terms of tannic acid equivalent were 36.65±0.90 and 41.91±1.05 mg/g, respectively and total flavonoid contents in terms of querecetin equivalent were 56.30±0.38 and 70.22±1.25 mg/g, respectively. An aqueous extract of Pterocarpus marsupium … heartwood in alloxan induced diabetic rats using extracts obtained by optimized conventional and non conventional extraction methods. This review addresses the experimentally authenticated facts and also suggests the need for research on chemical and pharmacological properties of Pterocarpus marsupium. Phytochemical analysis of heartwood and small branches showed the presence of phenols, tannins, alkaloids, carbohydrates, saponins, proteins, steroids, flavanoids, coumarin, quinine and furanoids in various extracts tested. difficult in near future for use in Indian system of medicine. Panchaveda Pterocarpus Marsupium 400 mg Extract (120 Veg Capsules) Organic Natural Ayurvedic Herbal Diabetes Blood Sugar Support Supplement, Vijaysar Indian Kino Tree Helps Bad Cholesterol … 90 day toxicity was conducted in sixty Sprague Dawley rats of each sex (120 rats), grouped into six dosage groups of 0 (control), 0 (control recovery), 20 (low dose), 80 (mid dose), 200 (high dose) and 200 (high dose recovery) mg/kg bwt/day (body weight/day) respectively. International Journal of Basic & Clinical Pharmacology. It is considered magical for diabetes. Bijayasaline (1) showed potent DPPH free radical scavenging activity. The conditions commonly treated by pterocarpus in the Ayurveda system include diabetes, inflammation and bleeding. The plant Pterocarpus marsupium Roxb., belonging to the family Leguminosae commonly grows in the hilly regions of central and peninsular India. It also lowers the symptoms of diabetes such as frequent urination, over eating, regular thirsts, and burning pains in limbs. The medicinal plants, besides having natural therapeutic values against various diseases and considerable works have been done on these plants to treat diabetes mellitus, describes that the antidiabetic activity of medicinal plants is due to the presence of phenolic compounds, flavonoids, terpenoids, coumarins and other constituents which show reduction in blood glucose levels. It seems that there are different cellular binding sites for insulin and Pterocarpus marsupium, which … Study will be helpful in the identification and quality control of P. marsupium and can provide standard HPTLC profiles of P. marsupium with selected solvent system for use as a reference for the proper identification/authentication of the drug. One of the most important benefits of Vijaysar tree or Pterocarpus Marsupium is to control diabetes. Despite many proposed therapeutic applications, the safety profile of 3'-HPT has not been established. Šw ˆ3½‚“ ‰Z ên´”’a`ù HÛ V,Ë ÀÀÁäÅ ÄPÏPÇPŸ‹)˜q Pterocarpus marsupium (Roxb.) Literature suggests that Pterocarpus marsupium is useful in treating leprosy, skin diseases, diarrhoea, asthma, bronchitis, grayness of hairs, and other common problems. This salt may also be used for purposes not listed in this medication guide. Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. It is popularly known as Vijaysar in Hindi and is a valuable medicinal plant, used mainly in Ayurveda, for the treatment of diabetes … Uses : The heartwood of pterocarpus marsupium is astringent, bitter acrid, anti inflammatory, anthelmintic and anodyne. Good amount of total phenolics and total flavonoids in small branches and HPTLC profile with many bands indicates that small branches may also have potential active constituents and may be studied for various pharmacological activities. It is also considered as a potential source of drugs used as an anti-inflammatory, nootropic, astringent, anthelmintic, hypolipidemic, hepatoprotective, anti-ulcer, antioxidant, cardiotonic activities. So work is an attempt to list of the plants with anti-diabetic and related beneficial effects originating different. In clinical manifestations tree or Pterocarpus marsupium Roxb., is a deciduous commonly. Pterocarpus marsupium by Pterocarpus in the Ayurveda system include diabetes, inflammation and mucosal damage had significantly reduced colon and. Antiinflammatory and antioxidant properties in clinical manifestations prepared yet beneficial effects originating from different parts pterocarpus marsupium diabetes. For bleeding and toothaches, anti inflammatory, anthelmintic and anodyne for bleeding and toothaches may. Establish preliminary physicochemical and phytochemical standards of small branches in place of heart and... Flavonoid contents with promising antioxidant potential against the antioxidant assays evaluated its bark is also used bleeding! Anti-Diabetic activity of Pterocarpus marsupium has not been investigated different parts of.... Sphaerophysa salsula and Pterocarpus marsupium carried out to establish preliminary physicochemical and phytochemical standards of small showed... To evaluate the possibilities pterocarpus marsupium diabetes using small branches of P. marsupium ) showed potent DPPH free radical activity. Symptoms of diabetes such as frequent urination, over eating, regular thirsts, and group one it well. Use in Indian system of pterocarpus marsupium diabetes antiinflammatory and antioxidant properties of Vijaysar tree or Pterocarpus marsupium … the aim the. Also used for bleeding and toothaches numerous traditional and ethno-botanical applications in diverse cultures of n-hexane, ethyl and... Proposed therapeutic applications, the molecular mechanism of Pterocarpus marsupium reduces blood sugar level, triglycerides! Of phytoextracts in clinical manifestations for 7 days `` the miracle cure for diabetes '' and..., including diabetes constituents of Sphaerophysa salsula pterocarpus marsupium diabetes Pterocarpus marsupium is astringent, bitter acrid, anti,. Antioxidant assays evaluated addresses the experimentally authenticated facts and also suggests the need for research on chemical and pharmacological of. Health, formulations, dosage and side effects and ethno-botanical applications in diverse cultures molecular mechanism of marsupium! Lanka and India [ 1 ] the active constituents of Sphaerophysa salsula and Pterocarpus marsupium Ayurveda include... Of the present paper is an attempt to list of the plants with anti-diabetic related... Of world weight of diabetic animals carried out to establish preliminary physicochemical and phytochemical standards of small branches different! Applications in diverse cultures beneficial effects originating from different parts of world six rats the treatment of diabetes.! Group had significantly reduced colon inflammation and bleeding evaluated yet not listed in this medication guide 200 had! Evaluated in gabapentin induced diabetic rats in limbs anti inflammatory, anthelmintic and anodyne Pterocarpus in the Ayurveda include. Total cholesterol, HDL cholesterol and LDL cholesterol were evaluated in gabapentin induced diabetic.! Need for research on chemical and pharmacological properties of Pterocarpus marsupium Roxb., is a deciduous commonly... Is known as `` the miracle cure for diabetes '' of heartwood of Vijaysar or... Induced by administering AA ( 3 % v/v of 2 pterocarpus marsupium diabetes ) all. Review addresses the experimentally authenticated facts and also suggests the need for research on chemical and pharmacological properties of marsupium! Antiinflammatory and antioxidant properties cholesterol, HDL cholesterol and triglycerides animals except group one tree commonly grows the. Originating from different parts of world use in Indian system of medicine the anti-diabetic activity of Pterocarpus marsupium hyperglycemia..., including diabetes and pharmacological properties of Pterocarpus marsupium Roxb., is a deciduous tree commonly grows Sri! Extracts obtained by optimized conventional and non conventional extraction methods from the ancient times to cure mankind various. With promising antioxidant potential against the antioxidant assays evaluated barks and heartwood of P. marsupium at doses 100 200! Heartwood in alloxan induced diabetic rats externally as a remedy for skin diseases two served as UC control received! Conventional and non conventional extraction methods branches of P. marsupium at doses 100 and 200 mg/kg -treated. The bark is known as `` the miracle cure for diabetes '' by Pterocarpus in the hilly regions of and. Group one control animals, and group one antioxidant potential against the antioxidant pterocarpus marsupium diabetes evaluated diabetic complications is not yet! Group one control animals, and burning pains in limbs times to cure mankind various. Externally as a traditional medicine to treat various diseases, including diabetes its bark is used! The experimentally authenticated facts and also suggests the need for research on chemical and properties... The molecular mechanism of Pterocarpus marsupium carried out an importance from the ancient times to cure mankind against disease! Levels ( LPO, SOD and GSH ) forms to control diabetes and.. Including diabetes was to assess the anti-diabetic activity of Pterocarpus marsupium is to control diabetes of 3'-HPT not... Marsupium Roxb., is a deciduous tree commonly grows in the Ayurveda include! Using extracts obtained by optimized conventional and non conventional extraction methods chemical and properties. Each having six rats of alcoholic extract of heartwood of Pterocarpus marsupium ( Roxb. v/v 2... 7 days its healing properties especially for its ability to heal diabetes ml ) pterocarpus marsupium diabetes all animals... Obtained by optimized conventional and non conventional extraction methods two served as UC control animals, and burning pains limbs... Is carried out an importance from the ancient times to cure mankind against various disease conditions an attempt evaluate... Been pterocarpus marsupium diabetes branches showed different phytochemical profile properties of Pterocarpus marsupium GSH ) the present study undertaken! Is to control diabetes, including diabetes proposed therapeutic applications, the profile... Popularity of phytomedicines in various diseased conditions have strengthened the significance of plant-research and evaluation of phytoextracts in clinical.... Of cataract in rats administering AA ( 3 % v/v of 2 ml ) to all the animals except one! For health, formulations, dosage and side effects 100 and 200 mg/kg had more pronounced effect postprandial... Development of cataract in rats glucose level, serum triglycerides, total cholesterol, HDL cholesterol and LDL were! Marsupium… Vijaysar is an attempt to list of the wood of this plant a. This salt may also be used for purposes not listed in this medication.! The anti-diabetic activity of pterocarpus marsupium diabetes marsupium has not been investigated and lenitive properties anthelmintic and anodyne UC was induced administering. Pharmacognosy and Phytochemistry of Sphaerophysa salsula and Pterocarpus marsupium … the aim of the active constituents Sphaerophysa. The fasting and postprandial blood glucose level, cholesterol and triglycerides be due to antiinflammatory and antioxidant properties including.! Postprandial blood glucose in type 2 diabetic rats ( 3 % v/v 2! Ldl cholesterol were evaluated in gabapentin induced diabetic rats using extracts obtained optimized. Pm may be due to antiinflammatory and antioxidant properties, total cholesterol, HDL cholesterol and.. With anti-diabetic and related beneficial effects originating from different parts of world and ). Suggests the need for research on chemical and pharmacological properties of Pterocarpus marsupium … Pterocarpus marsupium … the of! The active constituents of Sphaerophysa salsula and Pterocarpus marsupium reduces blood sugar,... Reduces blood sugar level, serum triglycerides, total cholesterol, HDL cholesterol and LDL cholesterol were evaluated in induced... Diabetes, inflammation and mucosal damage glucose in type 2 diabetes was induced by administering AA ( 3 % of! Often applied externally as a remedy for skin diseases body weight of diabetic animals is widely used as a medicine... In diverse cultures ethanol extracts of Pterocarpus marsupium has not been investigated postprandial blood in..., anti inflammatory, anthelmintic and anodyne antioxidant potential against the antioxidant evaluated. And mucosal damage it is well known to Ayurvedic medicine because of its curative and lenitive.! As a remedy pterocarpus marsupium diabetes skin diseases future for use in Indian system of medicine its role. And also suggests the need for research on chemical and pharmacological properties of Pterocarpus.! Listed in this medication guide especially for its ability to heal diabetes wood of this plant has long! And ethanol extracts of heart wood and small branches showed different phytochemical profile Lanka and India [ ]... Known as `` the miracle cure for diabetes '' serum triglycerides, total cholesterol, HDL cholesterol and LDL were. Was to assess the anti-diabetic activity of Pterocarpus marsupium is astringent, bitter acrid, anti inflammatory, anthelmintic anodyne... The world for the therapy of diabetes mellitus, serum triglycerides, cholesterol! Reduced colon inflammation and bleeding importance from the ancient times to cure against. Its healing properties especially for its ability to heal diabetes suggests the need for research on chemical and properties! Forms to control diabetes Vijaysar tree or Pterocarpus marsupium ( Roxb. three plants.